When Tom ruins Hildie and Beatie’s potions, they get fed up with him and he overhears them wanting a black cat instead of him. He makes and drinks a potion that turns him into a black cat, and they assume he’s another cat.
When Hildie and Beatie leaves their home, Tom and Jerry comes across Little Quacker who turns into a big monster on and off when he eats the stew that Tom made standing on the window.
Detectives Tom and Jerry discover Butch and a squirrel are stealing their business and later discover they are con artists and are stealing from customers.
When Hildie gets a magic mirror that predicts the future, Tom sees predictions of himself being fed a fish, which is good, and then a bad prediction: switching heads with Beatie.
Jerry and his friend Napoleon are lab mice and Tom is outside going through trash until he sees the two mice that he wants for an appetite and things go crazy when Dr. Bigby’s elderly cat becomes a vicious kitten and chases the mice.
Rick and Ginger go on a road trip to visit Ginger’s great aunt Claire, but on the trip, Spike and Tom get lost, and Spike deals with “The Doggie of Doom” who follows them.
Tom gets Spike sent to obedience school for being naughty, and Jerry is left without a protector. When Spike returns, Tom tries hard to get Spike to revert to his old ways. Jerry fights back to make sure that Spike keeps his cool.
Ginger gets a high-tech mattress and Tom is forbidden to sleep on it, but when Butch sees it and tries it out, it results in him, Tom, and Jerry fighting over the bed.
Detectives Tom and Jerry are hired by Polly the Dog to get back her collar from mean Barkley at the park. After a series of incidents involving the pound “jail” and an electric fence, Barkley reforms when he meets Polly and falls in love with her.
When a burglar has been breaking in homes, Rick and Ginger leave Spike in charge and Spike teaches Tom and Jerry how to protect their home and defend themselves.
Ginger and Rick decide to bring Tom and Spike along on their Hawaiian vacation, but on their plane flight, Jerry and Tuffy tag along as well. Tom and Spike get loose out of their cages, and before long, things go awry.
Dr. Bigby upgrades his robot to be “The future of home security,” but when Tom invades the lab to pursue Jerry and Napoleon, the robot has some tricks up its sleeves which will lead the robot into hysteria.
Tom has a date with Toodles and she warns him not to be late, but Butch tricks Tom that Toodles has a surprise in the basement for him and he leaves him down there; Toodles leaves Butch in charge of her younger, rowdy siblings; Jerry and Tuffy watches a horror movie and mistakes Tom for […]
Both Tom and Butch compete against to go after Ginger’s mom’s bird when her and Rick watch it for the weekend. Jerry also makes sure nothing happens to the bird.
When Hildie and Beatie go away on a vacation, Tom and Jerry has problems when their ghost nephew, Grayson, comes over and throws a large party with his friends and takes their crystal ball for bowling.
When Tom and Jerry go camping in Yosemite, Jerry appears to be having fun, but Tom is not. He tries to have as much fun as Jerry has, but ends up attracting a bear.
Spike develops allergies and Rick thinks that Spike is likely allergic to Tom, so Rick gets a hypoallergenic kitten named Glory for Ginger; Spike, Tom and Jerry plan to get rid of the nice kitten who is actually anything but and will do whatever it takes to be an only pet.
Toodles hires detectives Tom and Jerry to investigate and protect her against a threat to her Tuna can inheritance. They go investigate, and a mysterious and menacing figure keeps trying to hurt them.
Dr. Bigby creates cookies that give super strength and Jerry and Napoleon eat them and they have fun terrorizing Tom. He eventually gets revenge on them, however.
