On his birthday, Dexter makes himself invisible so that he can find out whether his parents have bought him the Major Glory action figure he always wanted.
Loading the player... During a trip to Japan as part of a student exchange program, Dexter accidentally releases a giant monster with an axe-like head from a volcano, forcing him to enlist the aid of his family to defeat it.
Dexter’s school and parents decide to send him to college. He ignores his fellow students, who prefer to “party now, study later”, until his mind finally snaps from the workload.
When Dee Dee tries to cut off a piece of her hair, she accidentally cuts off one of her pigtails. Dexter gives her a potion to make her missing hair grow back. However, Dee Dee squirts too much of it in her hair, and Dexter must return Dee Dee’s hair back to normal.
Dee Dee and her friends, Lee Lee and Mee Mee, enter Dexter’s lab and wreak havoc. Dexter clones himself to stop them, but the girls too make clones of themselves.
Dexter reluctantly takes piano lessons from Professor Williams (Paul Williams), but when the Professor stumbles onto Dexter’s lab, he discovers that Dexter has more musical talent than he thought.
In need of an assistant to operate his latest invention, Dexter performs a brain transplant on Dee Dee to make her smart enough to fulfill the role. With her new brain, Dee Dee proves to be more intelligent than Dexter.
Monkey’s birthday party is interrupted by Barbequor (Robert Ridgely), an intergalactic villain who plans to eat the planets, and his sidekick, the Silver Spooner (Rob Paulsen).
Dexter’s father is challenged to an arm wrestling match by a man named Earl at a truck stop. Stunned at the strength of Earl and his determination to beat his father, Dexter attaches a robotic arm to his father to enable him to win.
Suspicious that Dee Dee has not entered his lab even once on a particular day, Dexter shrinks himself and enters her room to spy on her. He soon becomes an unwilling character in Dee Dee’s doll story, but he believes the story to be real.
After Dee Dee declares that she can beat Dexter in any game, Dexter challenges her to a series of games in his lab, though he prefers to win by cheating.
Dexter’s new device allows him to study for the next day’s French test while sleeping. It malfunctions, causing a single phrase (omelette du fromage) to repeat throughout the night, causing Dexter to wake up the next morning speaking nothing else except omelette du fromage.
Dexter, Monkey, Agent Honeydew, the Justice Friends, Dee Dee, her imaginary friend Koosalagoopagoop, Mandark, his parents, and Dexter’s parents participate in a cross-country race a la Wacky Races.