Ginger gets a high-tech mattress and Tom is forbidden to sleep on it, but when Butch sees it and tries it out, it results in him, Tom, and Jerry fighting over the bed.

When Ginger’s wedding ring falls down the drain, Tom, Jerry and Spike have to get it back before she finds out.

Jerry and his friend Napoleon are lab mice and Tom is outside going through trash until he sees the two mice that he wants for an appetite and things go crazy when Dr. Bigby’s elderly cat becomes a vicious kitten and chases the mice.

Dr. Bigby creates cookies that give super strength and Jerry and Napoleon eat them and they have fun terrorizing Tom. He eventually gets revenge on them, however.

Dr. Bigby upgrades his robot to be “The future of home security,” but when Tom invades the lab to pursue Jerry and Napoleon, the robot has some tricks up its sleeves which will lead the robot into hysteria.

Spike develops allergies and Rick thinks that Spike is likely allergic to Tom, so Rick gets a hypoallergenic kitten named Glory for Ginger; Spike, Tom and Jerry plan to get rid of the nice kitten who is actually anything but and will do whatever it takes to be an only pet.

With eight of his nine lives gone, Tom uses magic in order to bring them back.

Rick and Ginger’s vacation continues on a cruise ship, where to make sure Tom and Spike don’t cause havoc, they keep them in the carriers. Jerry and Tuffy invade their vacation again, and Meathead, the ship’s cat, hunts down Jerry and Tuffy on the ship.

Spike forces Tom and Jerry to take over Tyke’s birthday party after they ruin it.

Tom is under strict orders to not wake the witch sisters, but Jerry is set on getting Tom in trouble. When Tom uses the magic spell wand and makes all of the furniture come alive, he must get the help of Newt to make everything go back as it was.

Both Tom and Butch compete against to go after Ginger’s mom’s bird when her and Rick watch it for the weekend. Jerry also makes sure nothing happens to the bird.

One of Dr. Bigby’s inventions make Tom intelligent.

One of Dr. Bigby’s inventions makes things float, so Jerry and Napoleon try it on themselves and then they try it out on Tom.