The U.S. army invades Dexter’s lab under the mistaken impression that aliens are using it as a base of operations on Earth, and Dexter must convince them that this is actually his lab, and also has to keep this a secret from Dee Dee.
Monkey must defend the city from a giant underground lava monster, Magmanamus (Brad Garrett), who cannot sleep because of the noise created by its residents.
With only one television in their apartment, Major Glory, Krunk, and Valhallen disagree on what to watch: Major Glory’s televised capture of the Disgruntled Postman, TV Puppet Pals, or the monster truck pull.
It is Career Day, and because Dexter is ashamed of his father, he creates a better father for himself. However, he soon discovers that his real father is much cooler.
After being denied dessert by his parents for not eating his vegetables, Dexter uses radiation therapy so that he can like vegetables, but it causes a severe side effect that turns him into an Incredible Hulk-like character if he goes too long without them.
In a parody of Tom and Jerry, Dexter accidentally switches his brain with that of a mouse’s and must avoid his mother when she decides to exterminate him.
Dexter catches the chicken pox, and Dee Dee tells him a ridiculous tale that if he keeps scratching them, he will turn into an evil chicken. Dexter completely restrains himself so that he will not have to scratch it; unfortunately, he is unable to resist and his nonstop scratching eventually does just that.
After fellow Justice Friend White Tiger helps Valhallen stop a super-villain, the latter invites him to spend the night in his apartment, forgetting that Major Glory is allergic to cats.
Dexter travels to the moon and finds that aliens are planning an invasion on Earth, and he uses his Robo-Dexo 2000 to stop them. It turns out that they only were interested in purchasing sweaters for the winter.
Dexter and Dee Dee enter tryouts to become Major Glory’s sidekick. When Dee Dee wins, Dexter realizes that fancy costumes are not the only criterion to become a superhero.
Dexter finds the exact opposite of his family, a hyperactive boy who is like Dee Dee and has scientist parents who are like Dexter. Sensing to fit in, he switches places with the boy.
Monkey’s birthday party is interrupted by Barbequor (Robert Ridgely), an intergalactic villain who plans to eat the planets, and his sidekick, the Silver Spooner (Rob Paulsen).
Dexter falls victim to one of his own inventions and sends Dee Dee back in time to warn his past self about the consequences, but the past Dexter proves hard to convince.