After watching an Action Hank movie on television, Dexter grows a synthetic beard to try to be cool, but the police mistake him for Action Hank himself.
In need of an assistant to operate his latest invention, Dexter performs a brain transplant on Dee Dee to make her smart enough to fulfill the role. With her new brain, Dee Dee proves to be more intelligent than Dexter.
When Dee Dee frees one of Dexter’s robots by removing the wrench that froze it, the robot tries to destroy anyone who is mean to Dee Dee, including her friends, her mother and Dexter himself.
Dexter makes his own Major Glory action figures so that he can join the neighborhood’s Major Glory gang, but gets into serious trouble when the rest of the gang finds out that none of his action figures are original.
On his birthday, Dexter makes himself invisible so that he can find out whether his parents have bought him the Major Glory action figure he always wanted.
Dexter and Koos must save Peepers to keep the land of Kooz from disappearing. However, they must contend with a villain who is determined to make the land of Kooz disappear forever.
Dee Dee accidentally shuts down Dexter’s lab, and he has to power it back. In the process, Dee Dee attempts to keep Dexter from finding out what she really did.
Dexter reluctantly takes piano lessons from Professor Williams (Paul Williams), but when the Professor stumbles onto Dexter’s lab, he discovers that Dexter has more musical talent than he thought.
To fix their apartment’s plumbing, Krunk and Valhallen go to the basement, where they meet Ratman (Maurice LaMarche), a diminutive vigilante raised by rats (a parody of Batman).
In a fit of rage, Dexter dumps Dee Dee’s favorite teddy bear into the garbage. An upset Dee Dee begins to behave oddly, prompting Dexter to go to the garbage dump and get it back.
Dexter creates a satellite to clean stains off of his clothes, but it goes horribly wrong when Mir space station hits the satellite that Dexter created and the satellite becomes damaged, causing the fabric beneath each stain to be eliminated as well.
When Dexter’s friends become tired of his complicated traps and cheating while playing a role-playing game, they put Dee Dee in his place. She changes the style of play, which annoys Dexter but impresses his friends.
Mandark disguises himself as Dexter’s mom to get into Dexter’s Lab. Unfortunately for Mandark, he now has to deal with Dexter, Dad, and Dee Dee’s requests, which are too much for him.