Detectives Tom and Jerry are hired by Polly the Dog to get back her collar from mean Barkley at the park. After a series of incidents involving the pound “jail” and an electric fence, Barkley reforms when he meets Polly and falls in love with her.

An unlucky dog named Dutch goes to Detectives Tom and Jerry, saying that a ruby stone he has been guarding from his great grandfather’s master pirate “Captain Wrongway Weston” is taken from a female dog named Roxy, who is also unlucky.

Both Tom and Butch compete for the Golden Fez in the United Mouse Catchers when they both attempt to capture Jerry.

Dr. Bigby upgrades his robot to be “The future of home security,” but when Tom invades the lab to pursue Jerry and Napoleon, the robot has some tricks up its sleeves which will lead the robot into hysteria.

After the plane incident, Rick and Ginger sneak Tom and Spike at “Paradise Resort” where pets are not allowed, but when Rick and Ginger leave Tom and Spike in their room, Jerry and Tuffy cause them trouble.

The witch sisters both commemorate the passing of their mother and Tom tries to help out by bringing her back from the grave.

Rick takes Tom and Spike to the vet for their checkup while Ginger hires an exterminator to get rid of Jerry and Tuffy.

While celebrating the holidays with Beatie and Hildie, Tom and Jerry destroy their Christmas tree and must go out to obtain a new one. In the process, they help out Santa Claus by delivering presents for Christmas.

Rick and Ginger’s vacation continues on a cruise ship, where to make sure Tom and Spike don’t cause havoc, they keep them in the carriers. Jerry and Tuffy invade their vacation again, and Meathead, the ship’s cat, hunts down Jerry and Tuffy on the ship.

Jerry gets affected by one of Dr. Bigby’s experiments that expresses love feelings and Tom tries to take advantage of Jerry’s loveable behavior.

Jerry and his friend Napoleon are lab mice and Tom is outside going through trash until he sees the two mice that he wants for an appetite and things go crazy when Dr. Bigby’s elderly cat becomes a vicious kitten and chases the mice.

One of Dr. Bigby’s inventions make Tom intelligent.

When Tom and Jerry go camping in Yosemite, Jerry appears to be having fun, but Tom is not. He tries to have as much fun as Jerry has, but ends up attracting a bear.

When he tries out a new cheese-in-a-can that Rick and Ginger buy, Tom has a crazy day when he experiences hallucinations based on the show’s other scenarios.

Butch tricks Tom into switching lifestyles while Jerry tries to endure Butch’s attempts to eat him.