Detectives Tom and Jerry are hired by Polly the Dog to get back her collar from mean Barkley at the park. After a series of incidents involving the pound “jail” and an electric fence, Barkley reforms when he meets Polly and falls in love with her.

Toodles hires detectives Tom and Jerry to investigate and protect her against a threat to her Tuna can inheritance. They go investigate, and a mysterious and menacing figure keeps trying to hurt them.

Spike develops allergies and Rick thinks that Spike is likely allergic to Tom, so Rick gets a hypoallergenic kitten named Glory for Ginger; Spike, Tom and Jerry plan to get rid of the nice kitten who is actually anything but and will do whatever it takes to be an only pet.

Tom and Jerry are locked out in the snow.

When Ginger’s wedding ring falls down the drain, Tom, Jerry and Spike have to get it back before she finds out.

Tom is under strict orders to not wake the witch sisters, but Jerry is set on getting Tom in trouble. When Tom uses the magic spell wand and makes all of the furniture come alive, he must get the help of Newt to make everything go back as it was.

Spike forces Tom and Jerry to take over Tyke’s birthday party after they ruin it.

When a burglar has been breaking in homes, Rick and Ginger leave Spike in charge and Spike teaches Tom and Jerry how to protect their home and defend themselves.

The witch sisters both commemorate the passing of their mother and Tom tries to help out by bringing her back from the grave.

Detectives Tom and Jerry are hired by Spike to find his missing bones.

Jerry and his friend Napoleon are lab mice and Tom is outside going through trash until he sees the two mice that he wants for an appetite and things go crazy when Dr. Bigby’s elderly cat becomes a vicious kitten and chases the mice.

Rick takes Tom and Spike to the vet for their checkup while Ginger hires an exterminator to get rid of Jerry and Tuffy.

When Tom ruins Hildie and Beatie’s potions, they get fed up with him and he overhears them wanting a black cat instead of him. He makes and drinks a potion that turns him into a black cat, and they assume he’s another cat.

When he tries out a new cheese-in-a-can that Rick and Ginger buy, Tom has a crazy day when he experiences hallucinations based on the show’s other scenarios.

An asteroid is heading towards earth and Tom and Jerry are determined to stop it; Napoleon is hungry for vending machine food.

Butch tricks Tom into switching lifestyles while Jerry tries to endure Butch’s attempts to eat him.