In an unsuccessful attempt to prove to Cow and Chicken that the Earth is flat, Dad brings in his brother, Professor Longhorn Steer, to teach them proper education.
It’s the Egyptian times, and Weasel and I.R. are both asp exterminators, attempting to save the queen Cleopantless (The Red Guy) from this infestation.
Cow and Chicken are feeling down, and visit their next door neighbor, who happens to be a famous blues musician. Through song, he tells them a wild tale.
Cow’s favorite toys, Crabs the Warthog, Piles the Beaver and Manure the Bear, make their escape out of the house on their own quest: to find “Maiden Hong Kong”.
Cow and Chicken are sent to join the Great Pantzini (the Red Guy’s) circus. He originally has Cow as a trapeze artist, and Chicken as a fire eater, but then settles to have them in as clowns.
Weasel works at a hotel as the manager, whereas I.R. is his incompetent bellhop. However, Weasel needs to rely on I.R.’s help when an acclaimed cannibal actor (The Red Guy) wants to eat him for dinner.