After fellow Justice Friend White Tiger helps Valhallen stop a super-villain, the latter invites him to spend the night in his apartment, forgetting that Major Glory is allergic to cats.

Created and narrated by a six-and-a-half-year-old boy named Tyler Samuel Lee, who sent a tape containing the episode’s audio to Cartoon Network,[9] the story follows Dexter and Mandark’s robot “brother” Computress teaming up to make Mandark’s head shrink.

Dee Dee builds a tree house and allows everyone inside except Dexter, in revenge for the times he kicked her out of his lab.

When Dexter’s glasses break, he creates a new fad (wearing broken glasses) and becomes extremely popular at his school.

Monkey must defend the city from a giant underground lava monster, Magmanamus (Brad Garrett), who cannot sleep because of the noise created by its residents.

While fighting Comrade Red and his gang, Krunk falls in love with his equivalent in their gang, She-Thing (Kath Soucie).

Dexter becomes the stern administrator of his local library.

Loading the player... Rerun of “Dexter’s Laboratory”, the first What a Cartoon! pilot.

Dexter creates a new type of ink that lets him command people to do whatever he wants. However, when Mandark gets his hands on it, Dexter is the one that becomes commanded.

Dexter’s parents remember their first date and dance together.

When his television show is interrupted by the Emergency Broadcast System, Dexter sets about fixing any emergencies in the neighborhood to make the signal go away.

Dee Dee’s father trains her to fight a gang of bicycle-riding rogues dressed as ninjas who target her paper route every morning.

Mandark enters a surfing contest and tries to cheat his way to victory to win Dee Dee’s heart from another surfer.

Parodying The Pink Panther, Dexter is trying to paint his lab blue, but Dee Dee wants to make it pink.

When Dexter catches Dee Dee killing ants, he shrinks them both to take her inside an ant colony so that she can learn how organized the ants are.

Dexter’s lab is threatened with repossession unless he can repay his debt to NASA. When Dee Dee wins the same amount in a lottery, he decides to steal her money out of desperation.

Dexter tries to move the Moon, which is blocking Saturn and its “science waves” (which is what makes it a “good day for science”).

Dexter and Dee Dee go to South America to catch the legendary chupacabra.

Dexter accidentally gives himself telepathy that he cannot shut off when trying to overhear his father’s thoughts to figure out what he got for his birthday, causing everyone to accidentally read his own mind.

Monkey’s birthday party is interrupted by Barbequor (Robert Ridgely), an intergalactic villain who plans to eat the planets, and his sidekick, the Silver Spooner (Rob Paulsen).

When his mother falls ill, Dexter creates a robot to do her chores. Dee Dee gets hold of its remote control and wreaks havoc, forcing Dexter to create a second robot to counter Dee Dee’s.

After watching a horror film, Dexter and his father become easily frightened.

To clone a dinosaur with an incomplete DNA sequence, Dexter uses his dog’s genetic code to fill in the gaps.

Dexter tries to turn himself into a superhero, but gives up after every power he tries backfires.

Dexter calls upon the “shoe gnomes” to repair his shoes, but he seeks out Dee Dee to rid himself of them afterwards.

When Dee Dee tries to cut off a piece of her hair, she accidentally cuts off one of her pigtails. Dexter gives her a potion to make her missing hair grow back. However, Dee Dee squirts too much of it in her hair, and Dexter must return Dee Dee’s hair back to normal.

Dexter tries to figure out how Dee Dee keeps entering his lab every time he kicks her out through one entrance and seals it.

Not interested in hearing Dee Dee’s long-winded story, Dexter gives her a silencing formula to keep her quiet, but it instead turns her into a giant monster still bent on telling her story. When he realizes that nothing can make her quiet, he becomes a giant monster himself.

Dexter turns Dee Dee into a boy, but is disappointed when “he” is not a genius as Dexter would like it.

Dexter creates a magnetic field to keep Dee Dee away from him, but it malfunctions, causing them to stick together.

Dexter catches the chicken pox, and Dee Dee tells him a ridiculous tale that if he keeps scratching them, he will turn into an evil chicken. Dexter completely restrains himself so that he will not have to scratch it; unfortunately, he is unable to resist and his nonstop scratching eventually does just that.

When Dee Dee causes Dexter to mistakenly take a book from the library without checking it out, they sneak into the library at night to put it back.