Upon seeing Tom unable to catch Jerry, Butch recruits the former to join the League of Cats, a secret organization of cats who work together to catch mice.
After the plane incident, Rick and Ginger sneak Tom and Spike at “Paradise Resort” where pets are not allowed, but when Rick and Ginger leave Tom and Spike in their room, Jerry and Tuffy cause them trouble.
While listening to his favorite hip hop music, Jerry gets disrupted by the noise of the city, so he moves out of town to a farm owned by Tom. As a result, his music causes Tom’s pet hen to lay eggs quickly.
When Jerry and Tuffy are planning to go on a vacation, Jerry gets mailed away when Tuffy forgets to bring a camera along with them, so Tuffy stays home and outwits Tom while Jerry attempts to come back home.
Little Quacker enlists Jerry’s help in getting his cracked favorite birdbath fixed, but they get distracted by the smell of Tom’s delicious Chinese takeout. After fighting over the food, Tom steals Little Quacker’s fortune cookie and gets the kind of fortune he deserves.
Detectives Tom and Jerry discover Butch and a squirrel are stealing their business and later discover they are con artists and are stealing from customers.
Ginger gets a high-tech mattress and Tom is forbidden to sleep on it, but when Butch sees it and tries it out, it results in him, Tom, and Jerry fighting over the bed.
A sequel to Pecos Pest (1955), Jerry’s uncle, Pecos Pest, returns to Tom and Jerry’s house for a visit, where he constantly sings and plays on his guitar, annoying and keeping both Tom and Jerry awake.
When Tom ruins Hildie and Beatie’s potions, they get fed up with him and he overhears them wanting a black cat instead of him. He makes and drinks a potion that turns him into a black cat, and they assume he’s another cat.