Astronauts John Jameson and Paul Stevens are sent to a newly discovered asteroid and discover a rock, known as “Promethium X”, which is said to be more powerful than plutonium. Unknown to them though, the “Promethium X” also contains a black, ooze-like creature, which manages to break free and tries to consume the two astronauts. […]

In a battle with Doctor Octopus, a medical research building is destroyed. Blaming himself, Peter is considering giving up being Spider-Man, when he meets an inter-dimensional being named Madame Web and his biggest fan, a little girl called Taina, who Spider-Man shares his origin story with. Doctor Octopus attacks with his new invention, the Octobot.

The symbiote returns to Earth and travels to Ravencroft to reunite with Brock, who then escapes as Venom. He is ordered by Dormammu and Baron Mordo, to whom the symbiote owes its earthly return, to steal a machine from Stark Enterprises capable of releasing Dormammu from his own far-off dimension.

When the crime lord Iceberg finds out that one of his gang members, Hobie, doesn’t feel that he is getting a fair cut, he has his boys attempt to kill him. After narrowly escaping that fate, Hobie steals a passer-by’s purse in order to fund his new trip. It turns out to be Mary Jane’s […]

An increasingly desperate Spider-Man drinks the serum designed to cure him, but it makes him grow four extra arms. The antihero known as the Punisher thinks Spider-Man is a crook and chases him around. Spider-Man finds out that Morbius has turned into a vampire and is draining people’s blood to survive. Spider-Man wants to help […]

The mutated Morbius is found by scientists and taken back to New York to have his condition studied. The Shocker kidnaps Morbius for Dr. Landon, who manages to revert Morbius back to his previous vampire form; however, in the confusion, Morbius escapes while Spider-Man fights his foes.

Spider-Man and Daredevil attempt to clear Peter’s name. Daredevil informs Spider-Man of Wilson Fisk’s true identity as the Kingpin. As Spider-Man battles the Chameleon, the stage is set for a fateful showdown between Daredevil and Kingpin.

Spider-Man and Blade put aside their differences in an attempt to prevent Morbius from using the Neogenic Recombinator to transform everyone into vampires like himself. They team up with Lt. Lee, who falls for Blade. During one attempt to stop Morbius, he kidnaps Peter’s aunt May and Felicia, causing Spider-Man and Blade to have a […]

When Osborn attempts to take over Toomes Aeronautical, Toomes becomes furious. He uses the Tablet of Time technology to steal youth from anyone he touches, becoming the Vulture to destroy Osborn.

The Spider-Men stop Spider-Carnage in his home dimension, but he escapes to another dimension, the one where Spider-Man is a billionaire. With limited power, Madame Web sends the main Spider-Man to this dimension, where he finds out his alternate counterpart is engaged to Gwen Stacy and finds Mary Jane alive. Peter then finds this reality’s […]

Norman Osborn hires Spencer Smythe to capture Spider-Man. Spencer creates his deadliest weapon, the Spider Slayer, to accomplish this, but he seemingly dies at the end of this episode in an explosion.

Trapped in the limbo between portals, the Green Goblin telepathically calls out to his son, Harry Osborn. Keeping his true identity a secret, he promises Harry that he will see his father soon if he becomes the second Green Goblin. Meanwhile, thinking Peter knows where Mary Jane is, Anna Watson unknowingly passes this information to […]

In Moscow, Silver Sable surprises Doctor Grotizick. In America, Keane Marlow surprisingly visits May, who introduces him to her nephew, Peter, explaining Keane was an old friend of his uncle Ben. Peter finds his parents’ old passports. He subsequently shows them to May, who orders Peter to put them away. Peter, however, eavesdrops on his […]

Angry over his son’s arrest and conviction, as well as Spider-Man now knowing his secret identity, to which he blames Alistair, Kingpin attempts to kill Spider-Man by turning Alistair into a cyborg to let him do it. Alistair’s father, Spencer, is revealed to have survived the explosion from the first season, but Kingpin has put […]

The Chameleon, an international spy, attempts assassination on two diplomats in order to derail the signing of a peace proposal. S.H.I.E.L.D. director Nick Fury enlists Jameson’s help to prevent the Chameleon’s crime, while Spider-Man begins his own hunt against the assassin.

Peter, returned to his old costume, soon comes across the Rhino and the Shocker, who manage to get the upper hand on him. However, an unknown “ally” arrives and defeats the two villains himself. The new “ally” is Brock, now known as Venom, who has bound to the discarded symbiote and wants revenge on Spider-Man.

Alistair, currently working as Silvermane’s top scientist, kidnaps the Black Cat. He then bribes Spider-Man into capturing either the Scorpion or the Vulture, whom both have unique DNA samples which are essential for Silvermane to restore his adulthood, in exchange for her release.