When a mysterious man known as Michael Korvac is discovered, the Avengers must figure out exactly what happened to him – all while defending him from the team of beings who have come after him: the Guardians of the Galaxy.
The Masters of Evil (now joined by Chemistro, the Grey Gargoyle, and the Living Laser) prepare for a full-scale invasion of Earth…and unless the Avengers can stop them, the legions of the Nine Realms are coming to Earth.
The Avengers are ambushed and captured, one by one, by Ultron’s team of synthezoid Avengers as part of the wayward android’s plan to rid the world of “flawed” humans, perfect himself, and construct a mate.
A mysterious explosion seemingly kills Hank Pym in his college laboratory, but as the Avengers and their friends mourn the loss of their fallen comrade-in-arms, a fearless new vigilante calling himself Yellowjacket – endowed with the same powers and technology as Ant-Man/Giant-Man and Wasp – begins taking out the members of the Serpent Society.
A.I.M.’s Scientist Supreme unleashes Technovore, providing a distraction for an armorless Tony Stark while the A.I.M. agents fight Black Panther, Captain America, and War Machine in an attempt to steal Stark Industries’ technology.
Nick Fury returns, having assembled a team of heroes in secret (himself, Black Widow, Mockingbird, and Quake) to gather information about the impending Skrull invasion of Earth.
The Leader has placed an expanding dome of pure gamma radiation around the Cube, with anyone caught inside it being mutated into a Gamma Monster. The Avengers, along with the support of S.H.I.E.L.D., enter the Cube in an attempt to the destroy the Gamma Generator.
With the Avengers, minus Ant-Man, turned into Gamma Monsters, Hawkeye must convince the Hulk to help fight the Leader and the Abomination while Thor (who was unaffected by the Gamma Dome) fights the Absorbing Man.
The Enchantress seeks revenge on Baron Zemo and the Masters of Evil for betraying her, and the remaining supervillains go to the Avengers for protection.
Kang the Conqueror revisits a time where Captain America and Bucky took down a HYDRA portal to Asgard as Kang believes Captain America is responsible for destroying Kang’s timeline.
After being a prisoner of the Skrulls for months, Captain America teams up with other prisoners, including some of his enemies, to escape. But in order to do so, they must first get past the mighty Super-Skrull…
A Kree ship led by Ronan the Accuser arrives and attacks a S.W.O.R.D. ship. While Abigail Brand fights the Kree soldiers in space, the Avengers are assisted by Ms. Marvel in fighting Ronan and an army of Kree soldiers on Earth.