Rick and Ginger go on a road trip to visit Ginger’s great aunt Claire, but on the trip, Spike and Tom get lost, and Spike deals with “The Doggie of Doom” who follows them.
Tom gets Spike sent to obedience school for being naughty, and Jerry is left without a protector. When Spike returns, Tom tries hard to get Spike to revert to his old ways. Jerry fights back to make sure that Spike keeps his cool.
Tom is under strict orders to not wake the witch sisters, but Jerry is set on getting Tom in trouble. When Tom uses the magic spell wand and makes all of the furniture come alive, he must get the help of Newt to make everything go back as it was.
When he tries out a new cheese-in-a-can that Rick and Ginger buy, Tom has a crazy day when he experiences hallucinations based on the show’s other scenarios.
Detectives Tom and Jerry are hired by Polly the Dog to get back her collar from mean Barkley at the park. After a series of incidents involving the pound “jail” and an electric fence, Barkley reforms when he meets Polly and falls in love with her.
A sequel to Pecos Pest (1955), Jerry’s uncle, Pecos Pest, returns to Tom and Jerry’s house for a visit, where he constantly sings and plays on his guitar, annoying and keeping both Tom and Jerry awake.
Both Tom and Butch compete against to go after Ginger’s mom’s bird when her and Rick watch it for the weekend. Jerry also makes sure nothing happens to the bird.
Jerry and his friend Napoleon are lab mice and Tom is outside going through trash until he sees the two mice that he wants for an appetite and things go crazy when Dr. Bigby’s elderly cat becomes a vicious kitten and chases the mice.
Ginger gets a high-tech mattress and Tom is forbidden to sleep on it, but when Butch sees it and tries it out, it results in him, Tom, and Jerry fighting over the bed.
Dr. Bigby upgrades his robot to be “The future of home security,” but when Tom invades the lab to pursue Jerry and Napoleon, the robot has some tricks up its sleeves which will lead the robot into hysteria.
