Dexter accidentally gives himself telepathy that he cannot shut off when trying to overhear his father’s thoughts to figure out what he got for his birthday, causing everyone to accidentally read his own mind.
Dexter catches the chicken pox, and Dee Dee tells him a ridiculous tale that if he keeps scratching them, he will turn into an evil chicken. Dexter completely restrains himself so that he will not have to scratch it; unfortunately, he is unable to resist and his nonstop scratching eventually does just that.
To learn more about girls, Dexter camouflages himself and enters Dee Dee’s room, where she is having a sleepover with her friends Lee Lee and Mee Mee. He gets caught by the girls, who force him to take part in their activities.
Dexter’s family goes to the beach, where Dexter tries to communicate with whales. He must rescue Dee Dee (dressed as a mermaid), when she is captured by manic pirates.
When his television show is interrupted by the Emergency Broadcast System, Dexter sets about fixing any emergencies in the neighborhood to make the signal go away.
Dexter is disappointed when he ends up at an Amish farm instead of a high-tech farm for summer camp. His attempts to modernize the Amish family do not go well.
Dad decides to give the car a retouch, but keeps breaking things and saying he will fix it later. After having enough, he pushes the car over a cliff, and below it are other crushed cars, meaning this was not the first time.
In a parody of Tom and Jerry, Dexter accidentally switches his brain with that of a mouse’s and must avoid his mother when she decides to exterminate him.
When Dexter is asked to bring his mother to school, he disguises Dee Dee as her so that she can take her place, but Dee Dee does not behave like their mother.
In need of an assistant to operate his latest invention, Dexter performs a brain transplant on Dee Dee to make her smart enough to fulfill the role. With her new brain, Dee Dee proves to be more intelligent than Dexter.
Dexter finds the exact opposite of his family, a hyperactive boy who is like Dee Dee and has scientist parents who are like Dexter. Sensing to fit in, he switches places with the boy.
Not interested in hearing Dee Dee’s long-winded story, Dexter gives her a silencing formula to keep her quiet, but it instead turns her into a giant monster still bent on telling her story. When he realizes that nothing can make her quiet, he becomes a giant monster himself.
Dexter and Mandark bring the Abraham Lincoln and George Washington faces respectively on Mount Rushmore to life and make them fight each other to determine who is the best.