Peter and Mary Jane arrive in Niagara Falls for their postponed honeymoon, but it is soon interrupted when Hydro-Man returns and kidnaps Mary Jane. With Black Cat’s help, Spider-Man sets off in pursuit.

Peter, with his powers enhanced by his new suit, focuses his attention on Brock and Jameson and warns the latter to call off his reward, also mentioning Rhino and how Brock neglected to mention him. Jameson finds out from John that Brock was lying and fires him. He also calls off the manhunt for Spider-Man. […]

Peter, returned to his old costume, soon comes across the Rhino and the Shocker, who manage to get the upper hand on him. However, an unknown “ally” arrives and defeats the two villains himself. The new “ally” is Brock, now known as Venom, who has bound to the discarded symbiote and wants revenge on Spider-Man.

When Peter arrives for a date with Felicia Hardy, she is kidnapped by corrupt scientist Doctor Octopus, in order to force her mother to provide him with ransom money in which she promised to fund his experiments. Complicating things, Peter recognizes the madman as Otto Octavius, his favorite science mentor from his childhood days.

Spider-Man grieves over Mary Jane’s loss following his battle against the Green Goblin. Meanwhile, Tombstone, whilst incarcerated in Ryker’s Island, plots revenge on Robbie for previously causing his arrest. In exchange for assisting cell-mate Richard Fisk in a few brawls in prison, Richard requests that his father frame Robbie as a criminal mastermind.

Spider-Man and Silver Sable track down Kragov, the Chameleon, and the Red Skull, but are caught in a force field. Apparently, the Doomsday Device the Skull created in the past was made to have Kravog turn into a “god”, being injected with electricity which allows him to create and manipulate electricity into doing his bidding. […]

Wilson Fisk, also known as the Kingpin, offers to provide Alistair Smythe with the funds he requires to build more of Spencer’s Spider-Slayer robots, claiming that Spider-Man is responsible for the death of his father. Alistair fails in his bid to kill Spider-Man and the others he holds responsible for his father’s death, and as […]

Angry over his son’s arrest and conviction, as well as Spider-Man now knowing his secret identity, to which he blames Alistair, Kingpin attempts to kill Spider-Man by turning Alistair into a cyborg to let him do it. Alistair’s father, Spencer, is revealed to have survived the explosion from the first season, but Kingpin has put […]

The symbiote returns to Earth and travels to Ravencroft to reunite with Brock, who then escapes as Venom. He is ordered by Dormammu and Baron Mordo, to whom the symbiote owes its earthly return, to steal a machine from Stark Enterprises capable of releasing Dormammu from his own far-off dimension.

While developing a new gas for Kingpin to use as a weapon, a mistake triggers an explosion and Osborn disappears in the chaos. A new villain, the Green Goblin, appears and kidnaps all of Osborn’s enemies. Felicia later meets with Spider-Man, tells him that she is in love with him, and passionately kisses him.

Peter and Robbie visit Omar Mosely, who tells them about the story of the Six American Warriors. During World War II, after the creation of Captain America, five more heroes were made: Whizzer, Miss America, the Thunderer, the Destroyer, and the Black Marvel. They fought alongside Captain America. Now in the present, Spider-Man must find […]

Crawford has developed a cure for Spider-Man’s disease, but she is reluctant to give an untested serum to him that may result in permanent loss of his powers or worse. After an angry outburst from Spider-Man, she hands it over. At the ESU lab, Peter is secretly observed by Felicia’s latest love interest, Michael Morbius, […]

With the Tablet of Time, Silvermane’s youth is restored, but he continues to grow younger until he finally becomes an infant. Surprisingly, the Tablet is also able to revert the Lizard back to Dr. Connors. As the ordeal has caused his wife Vanessa Fisk to leave him, Kingpin orders the Tablet gotten rid of which […]

Spider-Man and the Black Cat attempt to confront Kraven. After the latter eludes the two heroes, there are various reports of attacks. Debra Whitman decides to investigate and she, Black Cat, Flash Thompson, and Dr. Connors succeed in identifying the DNA as female. It turns out that Dr. Crawford had been given the same serum […]

As former sidekick of the late Black Marvel, Omar had hidden the Black Marvel’s keys after his death. Now aware of the Insidious Six’s theft of the majority of the keys, he was sure that they would search for them. Omar shows Robbie where the last keys are hidden. However, it unfolds to be the […]

After defeating the Red Skull, Spider-Man and the team attempt to rendezvous with the Fantastic Four, only to discover that they have been ambushed and that Doom has kidnapped the Thing. The heroes all go to rescue him, entering Doom’s empire, which they discover is a peaceful paradise. Doom used the technology of the planet […]

Osborn, still with the Goblin in control, tries to use the time dilation accelerator to find out Spider-Man’s secret identity. This leads to a fateful confrontation between Spider-Man and the Goblin that will change Peter’s life forever.

In Moscow, Silver Sable surprises Doctor Grotizick. In America, Keane Marlow surprisingly visits May, who introduces him to her nephew, Peter, explaining Keane was an old friend of his uncle Ben. Peter finds his parents’ old passports. He subsequently shows them to May, who orders Peter to put them away. Peter, however, eavesdrops on his […]

An ancient artifact known as the Tablet of Time has been uncovered. Kingpin wants to sell it, while elderly Silvermane wants to use it to restore his youth. Each crime lord kidnaps a useful hostage and a useless hostage.

Wolverine catches up with Spider-Man, who is hot on the trail of the missing Beast. Meanwhile, the Hobgoblin steals the mutant technology information that Landon had prepared for Kingpin. Meanwhile, Genevieve, Landon’s assistant, struggles with keeping her secret of being a telekinetic mutant, who saved Spider-Man from the collapsing ceiling.

After a confrontation with Miriam the Vampire Queen, Blade is horrified to learn that she was once his human mother. Using a psychic link, Miriam finds Morbius, who is fighting his vampire hunger, to find out what unconventional means he used to become one of her kind. Learning of the Neogenic Recombinator, Miriam plans to […]

Peter Parker / Spider-Man discovers that his science teacher, Dr. Curt Connors, has been turned into a deranged lizard due to an experiment gone wrong, and is abducting people throughout Manhattan.

Kingpin hires Rhino, Shocker, Doctor Octopus, Mysterio, Scorpion and the Chameleon to take down Spider-Man. Meanwhile, Peter has been experiencing brief periods of time where his powers temporarily vanish.

Peter and Mary Jane are ready to tie the knot. Their plans are interrupted, however, when the Scorpion kidnaps May. Spider-Man gives chase and rescues May, but wonders if the fates are trying to tell him something. Meanwhile, Kingpin is paying for Peter and Mary Jane’s wedding. When the wedding finally takes place, a still […]

As Peter goes to an interview with scientist Mariah Crawford, she is under attack by the villain Kraven the Hunter. After Spider-Man is able to elude him, Dr. Crawford explains that Kraven and her used to be in love but when he was seriously injured by lions she had no choice but to give him […]

Norman Osborn returns as the Green Goblin where he and the Hobgoblin, whom he considers an imposter, clash over Ohn’s time dilation accelerator. Meanwhile, Felicia is engaged to a smug playboy of whom Peter is greatly suspicious of.

Spider-Man and Daredevil attempt to clear Peter’s name. Daredevil informs Spider-Man of Wilson Fisk’s true identity as the Kingpin. As Spider-Man battles the Chameleon, the stage is set for a fateful showdown between Daredevil and Kingpin.

The mutated Morbius is found by scientists and taken back to New York to have his condition studied. The Shocker kidnaps Morbius for Dr. Landon, who manages to revert Morbius back to his previous vampire form; however, in the confusion, Morbius escapes while Spider-Man fights his foes.

Spider-Man and Blade put aside their differences in an attempt to prevent Morbius from using the Neogenic Recombinator to transform everyone into vampires like himself. They team up with Lt. Lee, who falls for Blade. During one attempt to stop Morbius, he kidnaps Peter’s aunt May and Felicia, causing Spider-Man and Blade to have a […]

Spider-Man begins to worry about his growing mutation. In order to seek a cure, he heads to the Xavier mansion, where he encounters the X-Men. A brief fight occurs, after which Spider-Man explains his plight to Charles Xavier, who tells Spider-Man that he cannot cure him. Beast tells Spider-Man to go to Herbert Landon, who […]

Spider-Man’s horrifying genetic mutation reaches its culmination as he transforms into the Man-Spider. Dr. Crawford summons Kraven to help her track down Spider-Man and cure him of his mutation with a newly developed antidote.

Madame Web brings Spider-Man to another dimension where he is brought before a being known as the Beyonder, who has chosen Spider-Man to be part of an experiment to see if good is more powerful than evil. He finds a paradise planet and chooses Doctor Octopus, Doctor Doom, Alistair, the Lizard, and the Red Skull […]